Retinal Vein Occlusion may be associated with increased risk of dementia

A study out of South Korea suggests that retinal vein occlusion (RVO) may be associated with increased risk of dementia. The coexistence of RVO with hypertension was found to be associated with a higher risk of dementia. In addition, RVO may be a predictor for dementia.

Neovascular AMD: Bevacizumab Injection Increases Angiogenic Biomarkers

Dr. Thiago Cabral

Neovascular age-related macular degeneration (nAMD) is induced by the development of new abnormal ‘leaky’ blood vessels in the choroid and retina, when the balance of pro- and anti-angiogenic factors is upset. Vascular endothelial growth factor (VEGF) is considered a critical modulator of angiogenesis and is related to induction of endothelial cell migration and proliferation after hypoxia. The development of anti-VEGF agents, such as bevacizumab (Avastin®), ranibizumab (Lucentis®) and aflibercept (Eylea®), revolutionized the treatment of nAMD.

Topical bromfenac reduces the frequency of intravitreal avastin in patients with branch retinal vein occlusion.

Topical bromfenac reduces the frequency of intravitreal bevacizumab in patients with branch retinal vein occlusion.

Increased lucentis dose does not offer additional benefit in retinal venous occlusions

from Wikipedia

Increasing the dose of ranibizumab (lucentis) did not offer any additional benefit in eyes with retinal vein occlusion, neither did laser photocoagulation improve vision or reduce edema significantly more than ranibizumab, according to the results of the RELATE study presented in Macula 2015. 

EYLEA gets FDA approval for wet AMD, Diabetic macular edema and macular edema following retinal vein occlusion

Regeneron Pharmaceuticals, Inc. has announced that Food and Drug Administration (FDA) has approved EYLEA (aflibercept) Injection for the treatment of Macular Edema following Retinal Vein Occlusion (RVO), which includes Macular Edema following Branch Retinal Vein Occlusion (BRVO) in addition to the previously-approved indication of Macular Edema following Central Retinal Vein Occlusion (CRVO).